Ginko Biloba
Ginkgo biloba is a herbal supplement derived from the leaves of the ginkgo tree and is commonly used to support cognitive function and circulation. It is thought to influence blood flow and antioxidant activity in the brain. People use ginkgo for memory, focus, and general mental performance, though results vary between individuals.
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This page summarizes anecdotal reports and community observations, not medical evidence. Reports may be incomplete, biased or inaccurate and are not medical advice or recommendations. “Risk” here refers to how frequently severe or prolonged symptom worsening is reported, not to proven causation or population-wide probability. Individual responses vary widely, and absence of issues in some users does not rule out significant reactions in others.
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Within PFS/PSSD/PAS communities, ginkgo is discussed in relation to its potential interactions with vascular and CNS signaling pathways. Most products use standardized leaf extracts (often framed around terpene lactones and flavone glycosides), and the general "use case" people cite is improved blood flow/microcirculation and antioxidant-type effects. Ginkgo can affect vascular tone and CNS arousal in some people. These mechanisms may interact with pathways involving vascular function, circulation, or CNS signaling that are often discussed in relation to PFS / PSSD / PAS.
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Mixed Outcomes Including Crash/ Flares of Symptoms & Minor Improvement in PFS/PSSD/PAS :
In community discussions, ginkgo is most often described as not moving the needle. Some people report transient improvements—slightly better erection quality, mild increase in genital blood flow sensation, or a subtle cognitive “brightness”—but these reports tend to be inconsistent and not durable. Many report no meaningful change at all. Severe or lasting worsening is not a common theme, but flares do get mentioned: headaches, jitteriness/anxiety, sleep disruption, feeling “wired,” or a general sense of being slightly off. When negative reactions are reported, they’re usually framed as reversible after stopping rather than a major baseline shift. The overall signal is “low-stakes, low-upside”: mostly neutral outcomes, occasional mild benefits, occasional mild flares.
Evidence Basis: General herbal pharmacology and clinical literature on ginkgo for cognition/circulation; anecdotal community reports (online forums, self-reports). No controlled studies establishing benefit for PFS/PSSD/PAS-specific outcomes.
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Sustained Lift / Improvement
Crash / Baseline Drop (Reported)
No Effect
Public comments reflect individual experiences and opinions. They are not medical advice and may not be accurate or representative.